No superheroes’ parents are more famous than Batman’s. Funny how this is true even as Mr. and Mrs. Wayne died in the very beginning of the original story. I guess their death is important as it served as a motivation to young Wayne to come Batman.
Even if Optimus Prime and his squad appeared in Ghostbusters, I doubt they would be able to take down the nefarious Stay Puft. It would take a Titan to do so, if a combiner if they are going to have any hope of kicking the giant marshmallow man’s butt.